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Patients should also be advised to discontinue therapy in case of severe vomiting or diarrhea
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In addition to human studies, in DdY mice fed with high-fat diet animal models, yerba maté has been suggested to promote satiety through various mechanisms, including induction and/or enhancement of intestinal glucagon-like peptide-1 (GLP-1), modulation of serum leptin levels and a possible direct central satiety-stimulatory effect [61]
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