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LINZESS is available in a once-daily dose for the following indications 1 For adults with IBS-C: 290 mcg For adults with CIC 2 dosing options: 145 mcg and 72 mcg For IBS-C in pediatric patients 7 years of age and older: 145 mcg For FC in pediatric patients 6 years of age and older: 72 mcg For IBS-C* ICD-10 Diagnosis Code K58.1 2,‡ For CIC* ICD-10 Diagnosis Code K59.04 2,‡ For FC † ICD-10 Diagnosis Code K59.04 2,‡ CIC, chronic idiopathic constipation

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Trelagliptin: first global approval